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Cleft lip and palate: Genes more important than thought?

Comparing 500,000 snippets of human DNA put scientists from the University of Bonn on the right track. A genetic variant on chromosome 8 occurs with significantly higher frequency in people with cleft lip and palate than in the control group. The results are to be published in the forthcoming issue of the journal Nature Genetics.

New study finds increased prevalence of left-handedness in children with facial development disorder

A new study by physician researchers from Hasbro Children's Hospital and Children's Hospital Boston has identified an increased prevalence in left-handedness in children with a congenital disorder known as hemifacial microsomia (HFM). The study was published in the March 2009 edition of the Journal of Craniofacial Surgery.

Plastic and reconstructive surgery ... in brief

New web-based research has quantified the attractiveness of the female form.

Scientists discover why teeth form in a single row

A system of opposing genetic forces determines why mammals develop a single row of teeth, while sharks sport several, according to a study published today in the journal Science. When completely understood, the genetic program described in the study may help guide efforts to re-grow missing teeth and prevent cleft palate, one of the most common birth defects.

Gene for cleft lip and palate identified

An international team of researchers has identified a gene variant that is a major contributor to oral clefts and triples the risk of recurrence in affected families, it was reported today in The New England Journal of Medicine. ''Cleft lip and cleft palate are among the most common birth defects in the United States,'' says Nancy S. Green, M.D., medical director of the March of Dimes, which helped fund the study. ''This new finding brings us closer to understanding the multiple genetic factors underlying these very serious birth defects, with probable environmental effects.''



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