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Alarming trend -- antiviral therapy to treat hepatitis C is declining in the US

Researchers from the University of Michigan determined that only 663,000 of the approximately 3.9 million Americans with hepatitis C virus (HCV) infection received antiviral therapy between 2002 and 2007. Treatment rates appear to be declining, in part because only half of the patients know they are infected.

Alcohol tolerance 'switch' found

Researchers at North Carolina State University have found a genetic "switch" in fruit flies that plays an important role in making flies more tolerant to alcohol.

UCSD researchers pave the way for effective liver treatments

A combination of bioengineering and medical research at the University of California, San Diego has led to a new discovery that could pave the way for more effective treatments for liver disease.

In this work, the researchers have utilized an array system that can identify the biological components that can lead to or alleviate liver disease.

Patients with cirrhosis and impaired cognitive abilities have more motor vehicle accidents

A recent study by Jasmohan Bajaj, M.D., and colleagues from Virginia Commonwealth University and McGuire VA Medical Center found that patients with cirrhosis of the liver who developed minimal hepatic encephalopathy (MHE) had a 16% rate of motor vehicle crashes compared to only 4% of those without MHE over one year.

Gene variant heightens risk of severe liver disease in cystic fibrosis

CHAPEL HILL, N.C. -- Researchers at the University of North Carolina at Chapel Hill have discovered a genetic risk factor for severe liver disease in people with cystic fibrosis.

Racial disparity studied in patients undergoing liver transplantation for hepatitis B

According to the Centers for Disease Control and Prevention (CDC) 1.5 to 2 million Americans are infected with the hepatitis B virus (HBV). Prior studies have shown there to be significant racial differences in access to and outcomes of liver transplantation. Recently, doctors from across the U.S.

Study finds adverse effects in treatment for primary sclerosing cholangitis

Primary sclerosing cholangitis (PSC) is an uncommon chronic liver disease characterized by progressive inflammation and destruction of the bile ducts. The disease progresses slowly, usually leading to biliary cirrhosis, portal hypertension and liver failure over a 10-15 year period.

Study shows carvedilol is effective in preventing variceal bleeding in cirrhotic patients

Patients with cirrhosis are at risk for developing portal hypertension that can lead to the formation, dilation, and rupture of esophageal varices. The annual incidence of esophageal varices is approximately 5% and one third of those will bleed.

Hepatitis C virus channels efforts into cell survival

Researchers at the University of Leeds have discovered a previously unknown mechanism that allows the hepatitis C virus (HCV) to remain in the body for decades.

New biomarker predicts response to hepatitis C treatment

DURHAM, N.C. -- Researchers have identified the first genetic marker that predicts response to hepatitis C treatments, and a single letter of DNA code appears to make a huge difference.

New genes at work in patients with hereditary lung disease

GAINESVILLE, Fla. -- University of Florida researchers have safely given new, functional genes to patients with a hereditary defect that can lead to fatal lung and liver diseases, according to clinical trial findings slated to appear this week in the online early edition of the Proceedings of the National Academy of Sciences.

Current hepatitis C treatments work equally well, UT Southwestern and national researchers report

DALLAS -- Aug. 6, 2009 -- The three treatment combinations for clearing the most common form of the hepatitis C virus work equally well with similar side effects, UT Southwestern Medical Center researchers and their colleagues in 13 other institutions have found.

Good news for some hard-to-treat hepatitis C patients

ST. LOUIS -- In a multi-center trial led by a Saint Louis University researcher, investigators found that a new combination therapy of daily consensus interferon and ribavirin helps some hepatitis C patients who have not responded to previous treatment.

Low-fat diet helps genetically predisposed animals avoid liver cancer

PHILADELPHIA -- In a study comparing two strains of mice, one susceptible to developing cancer and the other not, researchers found that a high-fat diet predisposed the cancer-susceptible strain to liver cancer, and that by switching to a low-fat diet early in the experiment, the same high-risk mice avoided the malignancy.



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