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UAB researchers discover antibody receptor identity, propose renaming immune-system gene

BIRMINGHAM, Ala. -- Researchers at the University of Alabama at Birmingham (UAB) have uncovered the genetic identity of a cellular receptor for the immune system's first-response antibody, a discovery that sheds new light on infection control and immune disorders.

UT Southwestern researchers examine mechanisms that help cancer cells proliferate

DALLAS -- Sept. 1, 2009 -- A process that limits the number of times a cell divides works much differently than had been thought, opening the door to potential new anticancer therapies, researchers at UT Southwestern Medical Center report in the Aug. 7 issue of the journal Cell.

Gene shut-down may offer early warning of chronic leukemia

COLUMBUS, Ohio -- A new study shows that certain genes are turned off early, before clinical signs of the disease appear, in the development of chronic leukemia.

The study, led by researchers at the Ohio State University Comprehensive Cancer Center - James Cancer Hospital and Solove Research Institute, examined cancer cells from patients with chronic lymphocytic leukemia (CLL) and from a

Silenced genes as a warning sign of blood cancer

In many types of cancer, parts of the genetic material of tumor cells are switched off by chemical labels called methyl groups. This kind of methyl labeling ranges among the epigenetic changes that do not change the sequence of DNA building blocks. Such labels are found particularly often in genes which act as important inhibitors of pathogenic cell growth.

Limited data suggest possible association between Agent Orange exposure

WASHINGTON -- A new report from the Institute of Medicine finds suggestive but limited evidence that exposure to Agent Orange and other herbicides used during the Vietnam War is associated with an increased chance of developing ischemic heart disease and Parkinson's disease for Vietnam veterans.

Green tea extract shows promise in leukemia trials

ROCHESTER, Minn. -- Mayo Clinic researchers are reporting positive results in early leukemia clinical trials using the chemical epigallocatechin gallate (EGCG), an active ingredient in green tea.

Study validates means to measure possible leukemia marker

COLUMBUS, Ohio - A study led by cancer researchers at The Ohio State University has validated a method for reliably measuring variations in certain proteins that may make good biomarkers in chronic leukemia patients.

Mayo Clinic-led researchers confirm gene variants associated with the most common adult leukemia

DENVER - A national team of researchers led by Mayo Clinic has found that patients with chronic lymphocytic leukemia (CLL) are more likely to have similar DNA changes or variants in up to six genes, compared to people who do not have the cancer.

New biomarker may predict leukemia aggressiveness

Scientists at the University of California, San Diego and the Moores UCSD Cancer Center have evidence of a potential new biomarker to predict the aggressiveness of an often difficult-to-treat form of leukemia.

Researchers Find Abnormal Cells in the Blood Years before Leukemia is Diagnosed

Researchers have shown that abnormal white blood cells can be present in patients’ blood more than six years prior to the diagnosis of a chronic form of lymphocytic leukemia.



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