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Molecule discovered that makes obese people develop diabetes

Many people who are overweight or obese develop insulin resistance and type 2 diabetes at some stage in their lives. A European research team has now discovered that obese people have large amounts of the molecule CXCL5, produced by certain cells in fatty tissue.

Study highlights from November issue of GIE: Gastrointestinal Endoscopy

OAK BROOK, Ill. -- November 23, 2009 -- In the November issue of GIE: Gastrointestinal Endoscopy, the monthly peer-reviewed scientific journal of the American Society for Gastrointestinal Endoscopy (ASGE), a study out of Stanford University found that Barrett's esophagus was detected in six percent of asymptomatic women undergoing endoscopic screening.

Largest gene study of childhood IBD identifies 5 new genes

In the largest, most comprehensive genetic analysis of childhood-onset inflammatory bowel disease (IBD), an international research team has identified five new gene regions, including one involved in a biological pathway that helps drive the painful inflammation of the digestive tract that characterizes the disease.

Anti-tumor necrosis factor treatment does not increase cancer Risk in RA patients

A recent study by Swedish researchers found that rheumatoid arthritis (RA) patients did not experience an elevated cancer risk in the first 6 years after starting anti-tumor necrosis factor (TNF

Study reveals possible link between IBD therapy and skin cancer

San Diego, CA (October 26, 2009) -- Findings from a new retrospective cohort study presented at the American College of Gastroenterology's 74th Annual Scientific meeting in San Diego indicate tha

Manipulating brain inflammation may help clear brain of amyloid plaques, Mayo Clinic researchers say

JACKSONVILLE, Fla. -- In a surprising reversal of long-standing scientific belief, researchers at the Mayo Clinic campus in Florida have discovered that inflammation in the brain is not the trigger that leads to buildup of amyloid deposits and development of Alzheimer's disease.

Stanford study identifies cellular mechanism that causes lupuslike symptoms in mice

STANFORD, Calif. -- Macrophages, the scavenger cells of the body's immune system, are responsible for disposing of dying cells. Stanford University School of Medicine researchers have identified one pathway in this important process in mice that, if disrupted, causes a lupuslike autoimmune disease.

Elevated lymphotoxin expression in liver leads to chronic hepatitis and causes HCC

A recent study maps the pathway that leads from infection with Hepatitis B and C virus (HBV and HCV) to chronic hepatitis and liver cancer and proposes a new therapeutic strategy for treating liver diseases with chronic inflammation.

Ulcerative colitis treatment reduces need for surgery by almost half

ROCHESTER, Minn -- A new study led by Mayo Clinic researchers has found that ulcerative colitis patients had a 41 percent reduction in colectomy after a year when treated with infliximab, according to a study published in the October 2009 issue of Gastroenterology.

University of Hawaii at Manoa CRCH scientists report adulthood body size associated with cancer risk

A team of scientists led by researcher Brenda Hernandez, Ph.D., M.P.H. -- an assistant professor at the University of Hawai'i at Mānoa's Cancer Research Center of Hawai'i -- has reported that body mass in younger and older adulthood, and weight gain between these life periods, may influence a man's risk for prostate cancer.

Prevent periodontitis to reduce the risk of head and neck cancer

PHILADELPHIA -- Chronic periodontitis, a form of gum disease, is an independent risk factor for head and neck squamous cell carcinoma. This suggests the need for increased efforts to prevent and treat periodontitis as a possible means to reduce the risk of this form of cancer.

Infections may lead to faster memory loss in Alzheimer's disease

ST. PAUL, Minn. -- Getting a cold, stomach bug or other infection may lead to increased memory loss in people with Alzheimer's disease, according to research published in the September 8, 2009, print issue of Neurology®, the medical journal of the American Academy of Neurology.

Mice can eat 'junk' and not get fat

A study in the September 4th issue of the journal Cell, a Cell Press publication, identifies a gene that springs into action in response to a high fat diet. Mice that lack the gene become essentially immune to growing obese, regardless of their eating habits.

U-M researchers find gene that protects high-fat-diet mice from obesity

ANN ARBOR, Mich.---University of Michigan researchers have identified a gene that acts as a master switch to control obesity in mice. When the switch is turned off, even high-fat-diet mice remain thin.

Inflammatory disease treatments will improve through the use of lipidomics

COLUMBIA, Mo. -- According to the National Center for Chronic Disease Prevention and Health Promotion, 46 million Americans have arthritis. Many of these people take over-the-counter anti-inflammatory medications that block production of certain molecules, known as bioactive lipids, to reduce pain and swelling.



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