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Umbilical cord blood as a readily available source for off-the-shelf, patient-specific stem cells

LA JOLLA, CA -- Umbilical cord blood cells can successfully be reprogrammed to function like embryonic stem cells, setting the basis for the creation of a comprehensive bank of tissue-matched, cord blood-derived induced pluripotent stem (iPS) cells for off-the-shelf applications, report researchers at the Salk Institute for Biological Studies and the Center for Regenerative Medicine in Barcelon

Scripps research scientists find missing puzzle piece of powerful DNA repair complex

LA JOLLA, CA -- September 30, 2009 ?Researchers at The Scripps Research Institute have found, crystallized, and biologically characterized a poorly defined component of a key molecular complex that helps people to avoid cancer, but that also helps cancer cells resist chemotherapy.

The research was published in the October 2, 2009 issue of the journal Cell.

Protein inhibitor helps rid brain of toxic tau protein

Tampa, FL (September 30, 2009) -- Inhibiting the protein Hsp70 rapidly reduces brain levels of tau, a protein associated with Alzheimer's disease when it builds up abnormally inside nerve cells affecting memory, neuroscientists at the University of South Florida found. The study is reported online today in the Journal of Neuroscience.

Survey: Men may not be adequately involved in decisions about prostate cancer screening

Men largely make decisions about prostate cancer screening based on conversations with their clinicians, but these discussions often do not include information about the risks of testing in addition to the benefits, according to a report in the September 28 issue of Archives of Internal Medicine, one of the JAMA/Archives journals.

Researchers believe hormone therapy should not be stopped prior to mammograms

(Boston) -- Researchers from Boston University School of Medicine (BUSM) are recommending that menopausal women on hormone therapy (HT) continue their treatment prior to having their annual mammogram screenings. These recommendations appear as an editorial in the current on-line issue of Journal of the North American Menopause Society.

Certain cancers more common among HIV patients than non-HIV patients

DALLAS -- Sept. 25, 2009 -- Researchers at UT Southwestern Medical Center have found that non-AIDS-defining malignancies such as anal and lung cancer have become more prevalent among HIV-infected patients than non-HIV patients since the introduction of anti-retroviral therapies in the mid-1990s.

UCI researchers create new strategy for highly-selective chemotherapy delivery

Irvine, Calif. -- UC Irvine researchers have created a new approach that vastly improves the targeting of chemotherapeutic drugs to specific cells and organs.

Lifestyle interventions in the prevention and treatment of cancer

Los Angeles, London, New Delhi, Singapore and Washington DC (September 24, 2009) There is clear evidence that lifestyle choices affect the incidence and treatment of cancer, according to a study published in the current issue of American Journal of Lifestyle Medicine (AJLM).

Scientists identify genetic cause of previously undefined primary immune deficiency disease

Researchers at the National Institutes of Health have identified a genetic mutation that accounts for a perplexing condition found in people with an inherited immunodeficiency.

Vaccination and testing for the human papilloma virus could eradicate cervical cancer

Berlin, Germany: Cervical cancer could be eradicated within the next 50 years if countries implement national screening programmes based on detection of the human papilloma virus (HPV), which causes the disease, together with vaccination programmes against the virus, according to a cervical cancer screening expert.

Excess body weight causes over 124,000 new cancers a year in Europe

Berlin, Germany: At least 124,000 new cancers in 2008 in Europe may have been caused by excess body weight, according to estimates from a new modelling study. The proportion of cases of new cancers attributable to a body mass index of 25kg/m2 or more were highest among women and in central European countries such as the Czech Republic, Latvia, Slovenia and Bulgaria.

Trial of new treatment for advanced melanoma shows rapid shrinking of tumors

Berlin, Germany: Researchers have made significant advances in the treatment of metastatic malignant melanoma -- one of the most difficult cancers to treat successfully once it has started to spread -- according to a study to be presented at Europe's largest cancer congress, ECCO 15 -- ESMO 34 [1], in Berlin on Thursday.

Therapeutic nanoparticles give new meaning to sugar-coating medicine

A research team at the National Institute of Standards and Technology (NIST) studying sugar-coated nanoparticles for use as a possible cancer therapy has uncovered a delicate balancing act that makes the particles more effective than conventional thinking says they should be.

Obesity hinders chemotherapy treatment in children with leukemia

PHILADELPHIA -- Obesity is an important factor contributing to chemotherapy resistance and increasing relapse rates among children with leukemia, according to recent findings published online first in Cancer Research, a journal of the American Association for Cancer Research.

Targeted heat therapy offers new standard treatment option for soft tissue sarcoma

Berlin, Germany: Patients with soft-tissue sarcomas at high risk of spreading were 30% more likely to be alive and cancer free almost three years after starting treatment if their tumours were heated at the time they received chemotherapy, according to new research. The finding bolsters the case for intensifying exploration of the strategy in other types of cancer.



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