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Cancer's distinctive pattern of gene expression could aid early screening and prevention

AUGUSTA, Ga. -- Distinctive patterns of genes turned off -- or left on -- in healthy versus cancerous cells could enable early screening for many common cancers and maybe help avoid them, Medical College of Georgia scientists say.

UCLA researchers discover new molecular pathway for targeting cancer, disease

A UCLA study has identified a way to turn off a key signaling pathway involved in physiological processes that can also stimulate the development of cancer and other diseases. The findings may lead to new treatments and targeted drugs using this approach.

Stealthy gene network makes brain tumors flourish

CHICAGO -- The brain tumor afflicting Sen. Edward Kennedy -- a glioblastoma -- is the most aggressive and wily form of brain cancer. It has foiled researchers' decades-long efforts to thwart its explosive growth in the brain. The lethal tumor ? the most common brain tumor in humans -- nimbly alters its genes like a quick-change artist to elude treatments to destroy it.

UAB researchers draft 3-D protein map to aid stroke, cancer research

BIRMINGHAM, Ala. -- A new three-dimensional computer protein map is helping researchers at the University of Alabama at Birmingham (UAB) unravel the biological pathways that control brain-cell death after a stroke.

Tumor suppressor gene in flies may provide insights for human brain tumors

SINGAPORE and DURHAM, N.C. -- In the fruit fly's developing brain, stem cells called neuroblasts normally divide to create one self-renewing neuroblast and one cell that has a different fate. But neuroblast growth can sometimes spin out of control and become a brain tumor.

Potential for non-invasive brain tumor treatment

DURHAM, N.C. -- Duke University engineers have taken a first step toward a minimally invasive treatment of brain tumors by combining chemotherapy with heat administered from the end of a catheter.

University of Cincinnati study finds needle biopsies safe in 'eloquent' areas of brain

CINCINNATI -- After a review of 284 cases, specialists at the Brain Tumor Center at the University of Cincinnati (UC) Neuroscience Institute have concluded that performing a stereotactic needle biopsy in an area of the brain associated with language or other important functions carries no greater risk than a similar biopsy in a less critical area of the brain.

Automated analysis of MR images may identify early Alzheimer?s disease

Analyzing MRI studies of the brain with software developed at the Martinos Center for Biomedical Imaging at Massachusetts General Hospital (MGH) may allow diagnosis of Alzheimer's disease and of mild cognitive impairment, a lesser form of dementia that precedes the development of Alzheimer's by several years.

Gene therapy could expand stem cells' promise

Once placed into a patient's body, stem cells intended to treat or cure a disease could end up wreaking havoc simply because they are no longer under the control of the clinician.

Computer model predicts brain tumor growth and evolution

PROVIDENCE, R.I. [Brown University] ? Researchers from Brown University and other institutions have developed a computational computer model of how brain tumors grow and evolve.

Lithium may help radiation target cancer, spare healthy tissue

Vanderbilt-Ingram Cancer Center investigators have uncovered a mechanism that helps explain how lithium, a drug widely used to treat bipolar mood disorder, also protects the brain from damage that occurs during radiation treatments.

New imaging analysis predicts brain tumor survival

ANN ARBOR, Mich. -- As early as one week after beginning treatment for brain tumors, a new imaging analysis method was able to predict which patients would live longer, researchers from the University of Michigan Comprehensive Cancer Center have found.

Reversing effects of altered enzyme may fight brain tumor growth

An international team of scientists from the Moores Cancer Center at the University of California, San Diego, the University of North Carolina and several institutions in China have explained how a gene alteration can lead to the development of a type of brain cancer, and they have identified a compound that could staunch the cancer's growth.

UNC study: Scientists identify chemical compound that may stop deadly brain tumors

CHAPEL HILL - Researchers at the University of North Carolina at Chapel Hill School of Medicine have identified a compound that could be modified to treat one of the most deadly types of cancer, and discovered how a particular gene mutation contributes to tumor growth.

Avastin effective at delaying brain tumor progression in recurrent disease

(SEATTLE) - The use of Avastin alone to treat a subgroup of recurrent Grade 3 brain tumors showed it was safe and effective at delaying tumor progression, according to a retrospective study of 22 patients conducted by a researcher at the Seattle Cancer Care Alliance.



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