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Greater certainty in monitoring 3 therapeutic medications is facilitated by new CRMs

Rockville, Md., November 18, 2009 -- To help bring greater certainty to the measurement of medication levels in a patient's bloodstream for three drugs with narrow therapeutic ranges, the U.S. Pharmacopeial Convention (USP) is releasing new certified reference materials (CRMs).

Shire presents study findings on its ADHD treatments at psychiatric meeting Oct 29-30

HONOLULU -- October 29, 2009 -- Shire plc (LSE: SHP, NASDAQ: SHPGY), the global specialty biopharmaceutical company, announced today that it will present key scientific data on its Attention-Defi

Autism Speaks' genetic resource exchange, tissue program support findings published in Nature

New York, NY (October 7, 2009) -- Autism Speaks' Autism Genetic Resource Exchange (AGRE) and the Autism Tissue Program (ATP) continue to play an integral role in continuing genetic research and new findings in the complex autism inheritance and causation puzzle.

UNC study pinpoints gene controlling number of brain cells

CHAPEL HILL -- In populating the growing brain, neural stem cells must strike a delicate balance between two key processes -- proliferation, in which the cells multiply to provide plenty of starting materials -- and differentiation, in which those materials evolve into functioning neurons.

Young adults may outgrow bipolar disorder

COLUMBIA, Mo. ?Bipolar disorder, or manic-depression, causes severe and unusual shifts in mood and energy, affecting a person's ability to perform everyday tasks. With symptoms often starting in early adulthood, bipolar disorder has been thought of traditionally as a lifelong disorder.

Schizophrenia gene linked with abnormal neurogenesis in adult and postnatal brain

Scientists now have a better understanding of a perplexing gene that is associated with susceptibility for a wide spectrum of severely debilitating mental illnesses.

Sleep patterns in children and teenagers could indicate risk for depression, researcher finds

DALLAS -- Aug. 13, 2009 -- Sleep patterns can help predict which adolescents might be at greatest risk for developing depression, a researcher at UT Southwestern Medical Center has found in a five-year study.

If bipolar disorder is over-diagnosed, what are the actual diagnoses?

Providence, RI -- A year ago, a study by Rhode Island Hospital and Brown University researchers reported that fewer than half the patients previously diagnosed with bipolar disorder received an actual diagnosis of bipolar disorder after using a comprehensive, psychiatric diagnostic interview tool --the Structured Clinical Interview for DSM-IV (SCID).

Vyvanse CII significantly improved ADHD symptoms for children 13 hours after administration

PHILADEPHIA -- July 22, 2009 -- Shire plc (LSE: SHP, NASDAQ: SHPGY), the global specialty biopharmaceutical company, today announced that a study published online in the peer-reviewed journal Child and Adolescent Psychiatry and Mental Health found once-daily Vyvanse® (lisdexamfetamine dimesylate) CII significantly reduced the symptoms of Attention-Deficit/Hyperactivity Disorder (ADHD) in chi

VYVANSE CII provided significant efficacy at 14 hours in adults with ADHD

Hollywood, FL -- July 1, 2009 -- Shire plc (LSE: SHP, NASDAQ: SHPGY), the global specialty biopharmaceutical company, today announced results from a Phase 3b study that found VYVANSE® (lisdexamfetamine dimesylate) CII demonstrated significant efficacy at 14 hours after administration during a simulated workplace environment study in adults with Attention Deficit Hyperactivity Disorder (ADHD).

Irritability should be considered when diagnosing bipolar disorder in children

EAST PROVIDENCE, RI -- A new study from Bradley Hospital and The Warren Alpert Medical School of Brown University, as well as two other institutions, adds to mounting evidence that clinicians consider irritability as a symptom when diagnosing pediatric bipolar disorder.

Much touted 'depression risk gene' may not add to risk after all

Stressful life events are strongly associated with a person's risk for major depression, but a certain gene variation long thought to increase risk in conjunction with stressful life events actually may have no effect, according to researchers funded by the National Institute of Mental Health (NIMH), part of the National Institutes of Health.

Specialty care costs for patients with bipolar disorder are higher than diabetes and other chronic diseases

SAN FRANCISCO -- Mayo Clinic researchers have found that bipolar disorder is more costly than other chronic conditions such as diabetes, depression, asthma or coronary artery disease. These findings are based on a review of health care claim costs. Specialty care costs (the costs of seeing any specialist and all tests ordered) were especially higher for bipolar patients.

Cognition already seriously impaired in first episode of schizophrenia

WASHINGTON -- Significant and widespread cognitive problems appear to exist in schizophrenia in its earliest phase, making it very hard for people with the disorder to work, study or be social, according to a new study published by the American Psychological Association.

New light on bipolar treatment drugs

Lithium has been established for more than 50 years as one of the most effective treatments for bipolar mood disorder.



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