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Tips from the Journals of the American Society for Microbiology

Bacterially Produced Antifungal on Skin of Amphibians May Protect Against Lethal Fungus

A second skin

Despite advances in treatment regimens and the best efforts of nurses and doctors, about 70% of all people with severe burns die from related infections. But a revolutionary new wound dressing developed at Tel Aviv University could cut that number dramatically.

US and European experts applaud new transatlantic task force on antibiotic resistance threat

Experts on both sides of the Atlantic applaud President Barack Obama and Swedish Prime Minister Fredrik Reinfeldt, representing the European Union (EU) Presidency, for establishing a transatlantic tas

Tips from the journals of the American Society for Microbiology

Genes May Determine Susceptibility to H5N1 Avian Influenza A Virus Infection

New old drug fights colon cancer

A new Tel Aviv University drug, based on an older generation antibiotic, may provide doctors with an effective and innovative method of treating colon cancer in both its incipient and full-blown stages ― and minimize the need for painful, uncomfortable colonoscopies and surgical polyp removal.

UBC researchers identify key behavior of immune response to Listeria

A team of University of British Columbia microbiologists has identified a key defence mechanism used by the immune system against Listeria with strong implications for the future development of vaccines.

Listeria is the bacteria that causes listeriosis, a food-borne infection that caused 22 deaths in Canada in an August 2008 outbreak in meat products produced by Maple Leaf Foods.

Aspirin misuse may have made 1918 flu pandemic worse

The devastation of the 1918-1919 influenza pandemic is well known, but a new article suggests a surprising factor in the high death toll: the misuse of aspirin. Appearing in the November 1 issue of Clinical Infectious Diseases and available online now, the article sounds a cautionary note as present day concerns about the novel H1N1 virus run high.

Master gene that switches on disease-fighting cells identified by scientists

The master gene that causes blood stem cells to turn into disease-fighting 'Natural Killer' (NK) immune cells has been identified by scientists, in a study published in Nature Immunology today. The discovery could one day help scientists boost the body's production of these frontline tumour-killing cells, creating new ways to treat cancer.

Beans' defenses mean bacteria get evolutionary helping hand

Bean plants' natural defences against bacterial infections could be unwittingly driving the evolution of more highly pathogenic bacteria, according to new research published today (10 September) in Current Biology.

Sickle cell study boosts call for improved childhood immunization programs in Africa

Children in Africa with sickle cell anaemia are dying unnecessarily from bacterial infections, suggests the largest study of its kind, funded by the Wellcome Trust. The results are published today in the journal the Lancet. The study has prompted calls for all children in Africa to receive vaccinations against the most common bacterial infections.

Shining a light on disease -- tracking light-emitting bacteria during infection

By attaching light-emitting genes to infectious bacteria in an experimental system, researchers at University College, Cork, Ireland, have been able to track where in the body the bacteria go -- giving an insight into the path of the infection process leading to the development of more targeted treatments.

Mounting a multi-layered attack on fungal infections

Unravelling a microbe's multilayer defence mechanisms could lead to effective new treatments for potentially lethal fungal infections in cancer patients and others whose natural immunity is weakened.

Safety, efficacy of corneal transplant procedure confirmed; an antibiotic can cause double vision

SAN FRANCISCO, CA?Highlights of September's Ophthalmology, the journal of the American Academy of Ophthalmology (Academy), include a 2009 review by the Academy of the safety and efficacy of a widely used corneal transplant procedure and a warning about an unusual but serious reaction to systemic fluroquinolones, a class of antibiotics used to treat a variety of bacterial infections.

Cannibalistic cells may help prevent infections, UT Southwestern researchers report

DALLAS -- Aug. 3, 2009 -- Infectious-disease specialists at UT Southwestern Medical Center have demonstrated that a cannibalistic process in cells plays a key role in limiting Salmonella infection.

Structure of antibiotic ramoplanin reveals promising mechanism

DURHAM, N.C. -- With the "last resort" antibiotic Vancomycin now plagued by the first signs of bacterial resistance, a scientific collaboration centered at Duke University has identified how a candidate successor antibiotic known as Ramoplanin A2 can kill pathogenic bacteria by interrupting how they form their cell membranes.



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