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Arthritis drug might prove effective in fighting the flu, study suggests

Researchers at the University of Maryland School of Medicine have found that an approved drug for treating rheumatoid arthritis reduces severe illness and death in mice exposed to the Influenza A virus.

Recent developments at Burnham Institute for Medical Research, May 2009

Human monoclonal antibodies effective against bird and seasonal flu viruses

MIT: New tissue scaffold regrows cartilage and bone

CAMBRIDGE, Mass.--MIT engineers and colleagues have built a new tissue scaffold that can stimulate bone and cartilage growth when transplanted into the knees and other joints.

UNC study: New approach promises greater success for predicting drug safety

CHAPEL HILL - Adverse reactions to drugs represent one of the leading causes of death in the United States. But there may be a way to predict who is most likely to suffer a toxic side effect to a drug before they have even taken it.

Women live longer, not better, largely because of obesity and arthritis

CHICAGO - Obesity and arthritis that take root during early and middle age significantly contribute to women's decreased quality of life during their senior years, according to researchers at Duke University Medical Center.

In a study that included 5,888 people over 65, women suffered up to two and a half times more disabilities than men of the same age.

Potential lung disease biomarkers yield clues to COX-2 inhibitor side effects

NEW YORK (April 29, 2009) -- In searching for a simple way to identify individuals with smoking-related lung injury, scientists at Weill Cornell Medical College have stumbled upon a potential explanation for why the class of pain-relievers known as COX-2 inhibitors increases the risk of heart problems among users.

Lice can be nice to us

Parasite infestations might have a good side. Wild mice from a Nottinghamshire forest have given experts at The University of Nottingham clues as to the importance of some parasites, such as lice, for the conditioning of a "natural" immune system.

Resolvins have the potential to resolve periodontal inflammation and restore tissue health

Periodontal (gum) disease is a chronic inflammation initiated by bacteria that affect the gums and bone supporting the teeth, and may eventually result in tissue and tooth loss. It is similar to other chronic inflammatory diseases such as arthritis, where inflammation causes tissue damage and is responsible for the disease.

Stroke survivors improve balance with tai chi

Stroke can impair balance, heightening the risk of a debilitating fall. But a University of Illinois at Chicago researcher has found that stroke survivors can improve their balance by practicing the Chinese martial art of tai chi.

TV crime drama compound highlights immune cells' misdeeds

St. Louis, March 20, 2009 -- Detectives on television shows often spray crime scenes with a compound called luminol to make blood glow. Researchers at Washington University School of Medicine in St. Louis have applied the same compound to much smaller crime scenes: sites where the immune system attacks the body's own tissues.

Researchers develop DNA 'patch' for canine form of muscular dystrophy

Using a novel genetic technology that covers up genetic errors, researchers funded in part by the National Institutes of Health have developed a successful treatment for dogs with the canine version of Duchenne muscular dystrophy, a paralyzing, and ultimately fatal, muscle disease.

Arthritis hinders physical activity for adults with heart disease

Arthritis affects more than half of adults with heart disease and appears to be a substantial barrier to utilizing physical activity to help manage their condition, according to a new Morbidity and Mortality Weekly Report (MMWR) study released today by the Centers for Disease Control and Prevention (CDC).

Inhibiting proteins may prevent cartilage breakdown in arthritis patients

COLUMBIA, Mo. ? Current arthritis medications can ease the pain, but stopping the progression of the disease requires more aggressive treatments: use of very limited available drugs or surgical intervention.

A Biomarker To Predict Osteoarthritis

A chronic degenerative joint disease, osteoarthritis (OA) is a common cause of pain and disability among older Americans. OA of the knee affects up to 6 percent of the older population, while OA of the hip affects about another 3 percent. While treatments vary, there is hope that early intervention -- before joint destruction can be clearly seen and measured on an X-ray image-will improve outcomes.

Study shows long-term use of NSAIDs causes severe intestinal damage

According to a study published today in the American Gastroenterological Association (AGA) journal Clinical Gastroenterology and Hepatology, chronic users of non-steroidal anti-inflammatory drugs (NSAIDs) have an increased risk of bleeding and visible damage to their small intestine. "We have always known that NSAIDs can cause potentially deadly stomach complications, but the extent of the impact on the small intestine was largely unknown until now," said David Graham, MD, lead study author. "The introduction of video capsule endoscopy gave us an opportunity to examine the small intestine and learn that NSAIDs can cause severe damage to this organ."



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