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Sun exposure may trigger certain autoimmune diseases in women

Ultraviolet (UV) radiation from sunlight may be associated with the development of certain autoimmune diseases, particularly in women, according to a study by researchers at the National Institute of Environmental Health Sciences (NIEHS), part of the National Institutes of Health.

Protein level may serve as predictor of severe osteoarthritis

Osteoarthritis (OA), the most common joint disorder throughout the world and a leading cause of disability, is characterized by pain, impaired joint mobility, reduction of muscular strength and loss of joint function. Unlike most other common diseases, little is known about its origins, and factors predicting a severe disease course have not been identified.

Immune responses to flu vaccine are diminished in lupus patients

Patients with the autoimmune disease systemic lupus erythematosus (SLE) have an increased risk of infection, due to both disturbances in their immune responses and treatment with immunosuppressive drugs.

Study aims to induce recovery from ankylosing spondylitis

Chinese patients will soon have the opportunity to take part in a study of a novel therapy aimed at reversing the autoimmune disease, ankylosing spondylitis.

Prehistoric cold case shows hints of interspecies homicide

DURHAM, N.C. -- The wound that ultimately killed a Neandertal man between 50,000 and 75,000 years was most likely caused by a thrown spear, the kind modern humans used but Neandertals did not, according to Duke University-led research.

NIH funds support UAB joint replacement research

BIRMINGHAM, Ala. -- Newly announced National Institutes of Health (NIH) funding will expand the reach of ongoing University of Alabama at Birmingham (UAB) research into a unique nanostructured coating to improve the performance and longevity of total joint replacement components.

Study to assess hip exercises as treatment for osteoarthritis in the knee joints

Researchers at Rush University Medical Center are testing a novel regimen of hip-muscle exercises to decrease the load on the knee joints in patients with osteoarthritis. The goal is not only to relieve pain but also, possibly, to halt progression of the disease.

Study demonstrates the anti-inflammatory properties of pine bark extract

(July 15, 2009) -- HOBOKEN, NJ -- A recent study published in International Immunopharmacology, reveals why Pycnogenol® (pic-noj-en-all), an antioxidant plant extract from the bark of the French maritime pine tree, is effective for reducing inflammation and soothing pain associated with various health problems. Dr.

Obesity contributes to rapid cartilage loss

OAK BROOK, Ill. -- Obesity, among other factors, is strongly associated with an increased risk of rapid cartilage loss, according to a study published in the August issue of Radiology.

Gene expression findings a step toward better classification and treatment of juvenile arthritis

Scientists have discovered gene expression differences that could lead to better ways to classify, predict outcome, and treat juvenile idiopathic arthritis (JIA).

New trigger for chronic inflammation in rheumatoid arthritis discovered

A signal molecule made by the human body that triggers the immune system into action may be important in rheumatoid arthritis, according to new research published today in Nature Medicine. The authors of the study, from Imperial College London, say that if scientists could block this signal, it may be possible to develop more effective arthritis treatments.

Anti-inflammatory drugs may defeat a treatment-resistant type of cancer

Effective drugs for treating a chemotherapy-resistant form of lymphoma might already be on the market according to a study that has pieced together a chemical pathway involved in the disease.

Johns Hopkins scientists out a gene for gout

Having partnered last year with an international team that surveyed the genomes of 12,000 individuals to find a genetic cause for gout, Johns Hopkins scientists now have shown that the malfunctioning gene they helped uncover can lead to high concentrations of blood urate that forms crystals in joint tissue, causing inflammation and pain -- the hallmark of this disease.

Psoriasis associated with cardiovascular disease and increased mortality

The skin disease psoriasis is associated with atherosclerosis (a buildup of plaque in the arteries) characterized by an increased prevalence of ischemic heart disease, cerebrovascular disease, peripheral artery disease and an increased risk of death, according to a report in the June issue of Archives of Dermatology, one of the JAMA/Archives journals.



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