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Research finds photos more useful than words

(Boston) - Researchers from Boston University School of Medicine (BUSM) have found that pictures allow patients with very mild Alzheimer's disease (AD) to better recognize and identify a subject as compared to using just words. In addition, the researchers found that these patients can rely on a general sense of knowing or familiarity but not recollection to support successful recognition.

SUMO protein guides chromatin remodeler to suppress genes

BOSTON (April 27, 2009) --In an in vitro study, led by Grace Gill, PhD, Tufts University School of Medicine, researchers discovered how a protein called SUMO (Small Ubiquitin-related Modifier) guides an enzyme complex that alters the structure of chromatin to regulate expression of genes. Chromatin is a compacted mass of DNA and protein that make up chromosomes.

Humanin peptide linked to neuronal cell survival and regulation of glucose metabolism

Recent studies have shown that the mitochondrial peptide Humanin (HN) protects against neuronal cell death such as happens in Alzheimer's disease.

Exercise protects against damage causing leakage in the blood-brain barrier

Regular exercise can prevent the disruption of the blood brain barrier that normally occurs with a dose of methamphetamine comparable to that used by heavy meth users.

Alzheimer cell death in Zebrafish: Demise of neurons observed live for the first time

Extensive death of nerve cells leads to severe dementia in patients with Alzheimer's disease. Until now, it has only been possible to investigate the neuronal devastation in post mortem animal models, and by using complicated methods.

Test quickly assesses whether Alzheimer's drugs are hitting their target

A test developed by physician-scientists at Washington University School of Medicine in St. Louis may help assess more quickly the ability of Alzheimer's drugs to affect one of the possible underlying causes of Alzheimer's disease in humans, accelerating the development of new treatments.

Building a Stronger Brain

April 7, 2009 by mcole

Mental activity is an important way to develop a stronger, healthier brain through the building of Brain Reserve. Brain Reserve relates to the brain’s ability to physically reorganize itself in response to the demands placed upon it. A brain with a strong Reserve is one that has formed many cellular connections and is rich in brain cell density.

Young adults at future risk of Alzheimer's have different brain activity, says study

Young adults with a genetic variant that raises their risk of developing Alzheimer's Disease show changes in their brain activity decades before any symptoms might arise, according to a new brain imaging study by scientists from the University of Oxford and Imperial College London.

Progress toward an Alzheimer's drug that saves brain cells

Leuven - VIB scientists connected to the K.U.Leuven have identified a molecule that can form the basis for a new therapy for Alzheimer's disease. This is the first step toward a medicine that could actually stop the progress of Alzheimer's. Existing medicines can at best limit the loss of memory during the first phases of the disease.

Study finds how brain remembers single events

Irvine, Calif., March 18, 2009 - Single events account for many of our most vivid memories - a marriage proposal, a wedding toast, a baby's birth. Until a recent UC Irvine discovery, however, scientists knew little about what happens inside the brain that allows you to remember such events.

Alzheimer's, Autism & the NCAA: Science News for 3/17

March 17, 2009 by coglanglab

coglanglab's picture

Do vaccines give Somalis autism? Can diabetes give you Alzheimer's? Does losing make you win? Anyone scanning the science news articles this week would know the answers to these questions.

Mechanism of Alzheimer's suggests combination therapy needed

Researchers at the University of Illinois at Chicago College of Medicine have discovered a mode of action for mysterious but diagnostic protein snarls found in the brains of Alzheimer's patients that suggests a one-two punch of therapy may be needed to combat the neurodegenerative disease.

Alzheimer's disease therapeutic prevents long-term damage from TBI in pre-clinical studies

WASHINGTON, D.C. - A class of Alzheimer's disease drugs currently studied in clinical trials appears to reduce damage caused by traumatic brain injury in animals, researchers at Georgetown University Medical Center report in an upcoming advance online publication of Nature Medicine.

Study suggests blood test for Alzheimer's possible

Researchers have revealed a direct relationship between two specific antibodies and the severity of Alzheimer's disease symptoms, raising hopes that a diagnostic blood test for the devastating disorder is within reach.



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