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Scientists locate disease switches

A team led by Professor Matthias Mann of Novo Nordisk Center for Protein Research at the University of Copenhagen and the Max Planck Institute for Biochemistry in Germany has detected 3,600 acetylation switches in 1,750 different proteins.

Barrow researchers identify new brain receptor, possible target for Alzheimer's treatment

Barrow Neurological Institute researchers have identified a novel receptor in the brain that is extremely sensitive to beta-amyloid peptide (AB) and may play a key role in early stages of Alzheimer's disease.

Published in the Journal of Neuroscience, the research lead by Jie Wu, MD, PhD, has identified a new candidate for therapeutic intervention in Alzheimer's.

Alzheimer's risk: Would you want to know?

ANN ARBOR, Mich.---When people learn they are predisposed to Alzheimer's disease, any depression or anxiety is not long lasting, a new study indicates.

Vitamin D, curcumin may help clear amyloid plaques found in Alzheimer's disease

UCLA scientists and colleagues from UC Riverside and the Human BioMolecular Research Institute have found that a form of vitamin D, together with a chemical found in turmeric spice called curcumin, may help stimulate the immune system to clear the brain of amyloid beta, which forms the plaques considered the hallmark of Alzheimer's disease.

Memory test and PET scans detect early signs of Alzheimer's

Berkeley -- A large study of patients with mild cognitive impairment revealed that results from cognitive tests and brain scans can work as an early warning system for the subsequent development of Alzheimer's disease.

Pesticide levels in blood linked to Parkinson's disease, UT Southwestern researchers find

DALLAS -- July 13, 2009 -- People with Parkinson's disease have significantly higher blood levels of a particular pesticide than healthy people or those with Alzheimer's disease, researchers at UT Southwestern Medical Center have found.

Mount Sinai researchers find new Alzheimer's disease treatment promising

(New York, NY -- July 12, 2009) -- Researchers at Mount Sinai School of Medicine have found that a compound called NIC5-15, might be a safe and effective treatment to stabilize cognitive performance in patients with mild to moderate Alzheimer's disease. The two investigators, Giulio Maria Pasinetti, M.D., Ph.D.

Results from trials of DHA in Alzheimer's disease and age-related cognitive decline

Vienna, July 12, 2009 -- Results from two large studies using DHA, an omega 3 fatty acid, were reported today at the Alzheimer's Association 2009 International Conference on Alzheimer's Disease (ICAD 2009) in Vienna.

Research may hold key to maintaining embryonic stem cells in lab

DALLAS -- July 9, 2009 -- In a new study that could transform embryonic stem cell (ES cell) research, scientists at UT Southwestern Medical Center have discovered why mouse ES cells can be easily grown in a laboratory while other mammalian ES cells are difficult, if not impossible, to maintain.

Hitting cell hot spot could help thwart Parkinson's disease

The latest work to 'turn off the taps' in the brain and stop a chemical being released in excess amounts -- which can lead to Parkinson's Disease -- will be presented at The British Pharmacological Society's Summer Meeting in Edinburgh today (Wednesday, 8 July 2009).

Blood stem cell growth factor reverses memory decline in mice

Tampa, FL (July 1, 2009) -- A human growth factor that stimulates blood stem cells to proliferate in the bone marrow reverses memory impairment in mice genetically altered to develop Alzheimer's disease, researchers at the University of South Florida and James A. Haley Hospital found.

University of Houston research team aims to help caregivers monitor patients' health and whereabouts

For those who are caring for elderly parents, peace of mind is hard to come by. And, for their parents, dignity is hard to retain. But a team of University of Houston researchers hopes to ease worries and frustrations by designing an affordable in-home health-monitoring system that will notify caregivers, via smartphones or PDAs, if their loved ones need attention.

Measuring brain atrophy in patients with mild cognitive impairment

Scientists at the University of California, San Diego School of Medicine have shown that a fully automated procedure called Volumetric MRI -- which measures the "memory centers" of the brain and compares them to expected size -- is effective in predicting the progression from mild cognitive impairment (MCI) to Alzheimer's disease.

Another McGill/JGH breakthrough opens door to early Alzheimer's diagnosis

A new diagnostic technique which may greatly simplify the detection of Alzheimer's disease has been discovered by researchers at McGill University and the affiliated Lady Davis Institute for Medical Research at Montreal's Jewish General Hospital (JGH). Their results were published June 8 in the Journal of Alzheimer's Disease.

New data demonstrate potential for early detection of Alzheimer's disease

MONTREAL, CANADA, JUNE 16, 2009 -- Data published in the June issue of the Journal of Alzheimer's Disease demonstrated that minimally-invasive biospectroscopy was able to identify changes in oxidative stress (OS) levels in blood plasma, which may prove to be a useful biomarker in the early detection of Alzheimer's disease.



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