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U-M discovery about biological clocks overturns long-held theory

ANN ARBOR, Mich.---University of Michigan mathematicians and their British colleagues say they have identified the signal that the brain sends to the rest of the body to control biological rhythms, a finding that overturns a long-held theory about our internal clock.

New findings about brain proteins suggest possible way to fight Alzheimer's

DALLAS -- Oct. 6, 2009 -- The action of a small protein that is a major villain in Alzheimer's disease can be counterbalanced with another brain protein, researchers at UT Southwestern Medical Center have found in an animal study.

UBC researchers identify key behavior of immune response to Listeria

A team of University of British Columbia microbiologists has identified a key defence mechanism used by the immune system against Listeria with strong implications for the future development of vaccines.

Listeria is the bacteria that causes listeriosis, a food-borne infection that caused 22 deaths in Canada in an August 2008 outbreak in meat products produced by Maple Leaf Foods.

Half-million low-income elderly affected by sweeping cuts to state safety net

An 81-year-old San Francisco woman with dementia, little money and an equally aged caregiver sister who is suffering from cancer.

A 72-year-old Riverside woman with Alzheimer's who cannot be left safely on her own, forcing her son to cut back his working hours to care for her.

Risk of abnormally slow heart rate twice as high in those taking drugs to slow Alzheimer's

TORONTO, Ont., October 1, 2009 -- People taking one of several drugs commonly prescribed to treat Alzheimer's disease are more likely to be hospitalized for a potentially serious condition called bradycardia than patients not taking these medications.

Protein inhibitor helps rid brain of toxic tau protein

Tampa, FL (September 30, 2009) -- Inhibiting the protein Hsp70 rapidly reduces brain levels of tau, a protein associated with Alzheimer's disease when it builds up abnormally inside nerve cells affecting memory, neuroscientists at the University of South Florida found. The study is reported online today in the Journal of Neuroscience.

Extra virgin olive oil compound may help prevent, treat Alzheimer's

PHILADELPHIA (September 29, 2009) -- Oleocanthal, a naturally-occurring compound found in extra-virgin olive oil, alters the structure of neurotoxic proteins believed to contribute to the debilitating effects of Alzheimer's disease. This structural change impedes the proteins' ability to damage brain nerve cells.

Impaired kidney function linked to cognitive decline in elderly

A new study published in the medical journal Neurology suggests that impaired kidney function is a risk factor for cognitive decline in old age.

Sleep loss linked to increase in Alzheimer's plaques

Chronic sleep deprivation in a mouse model of Alzheimer's disease makes Alzheimer's brain plaques appear earlier and more often, researchers at Washington University School of Medicine in St. Louis report online this week in Science Express.

They also found that orexin, a protein that helps regulate the sleep cycle, appears to be directly involved in the increase.

University Hospitals Case Medical Center to test gammaglobulin treatment for Alzheimer's disease

Researchers from the Memory and Cognition Center at University Hospitals Case Medical Center will begin testing an intriguing new approach to slowing down the progression of Alzheimer's Disease (AD) using Intravenous Immune Globulin (IGIV), also known as gammaglobulin.

How mitochondrial gene defects impair respiration, other major life functions

Researchers are delving into abnormal gene function in mitochondria, structures within cells that power our lives. Mitochondria are the place where energy is generated from the most basic molecules of food. Because this function is essential to life, defects in mitochondria may affect a wide range of organ systems in humans and animals.

Historic gene therapy trial to treat Alzheimer's disease underway at Georgetown

Washington, DC -- Researchers in the Memory Disorders Program at Georgetown University Medical Center are now recruiting volunteers for a national gene therapy trial -- the first study of its kind for the treatment of patients with dementia due to Alzheimer's disease.

Problems managing money may surface shortly before Alzheimer's disease sets in

ST. PAUL, Minn. -- New research finds poor money management skills may indicate that a person with mild memory problems will soon develop Alzheimer's disease. The study is published in the September 22, 2009, print issue of Neurology®, the medical journal of the American Academy of Neurology.

Poor money management may be early indicator of Alzheimer's disease, say UAB researchers

BIRMINGHAM, Ala. -- Inability to handle financial transactions or manage money may be an early indicator that a person with mild memory problems soon is likely to develop Alzheimer's disease, according to new research from the University of Alabama at Birmingham (UAB) Alzheimer's Disease Center, part of the Department of Neurology.

Ben-Gurion University Alzheimer's researcher demonstrates specific immune response to vaccine

BEER-SHEVA, September, 21 2009 -- A researcher who is working on a vaccine for Alzheimer's disease (AD) has demonstrated that it is possible to test and measure specific immune responses in mice carrying human genes and to anticipate the immune response in Alzheimer's patients.



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