machinery
From the valves in a human heart to the quills on a porcupine to the petals on a summer lily, the living world is as varied as it is vast. For this to be possible, the cells that make up these living things must be just as varied. Parent cells must be able to divide in ways that create daughter cells that are different from each other, a process called asymmetric division.
In the quest for new approaches to treating and preventing disease, one appealing route involves turning genes on or off at will, directly intervening in ailments such as cancer and diabetes, which result when genes fail to turn on and off as they should.
Scientists at the University of Michigan and the University of California at Berkeley have taken a step forward on that route by developing sm
ANN ARBOR, Mich.---In the quest for new approaches to treating and preventing disease, one appealing route involves turning genes on or off at will, directly intervening in ailments such as cancer and diabetes, which result when genes fail to turn on and off as they should.
MADISON -- It's hard to miss the huge eye of a squid. But now it appears that certain squids can detect light through an organ other than their eyes as well.
That's what researchers at the University of Wisconsin-Madison report in the current issue (June 2) of the Proceedings of the National Academy of Sciences.
It turns out that from the perspective of cell biology, Nietzsche may have been right after all: that which does not kill us does make us stronger.
In collaboration with the Chinese Academy of Sciences in Beijing, scientists have investigated the rotation of molecules on a fixed surface to understand how they may help in the development of future rotor-based machinery at nanoscale level.
Neurosensory diseases are difficult to model in mice because their symptoms are complex and diverse. The genetic causes identified are often lethal when transferred to a mouse. The lack of animal models slows progress in understanding and treating the diseases.
GAINESVILLE, Fla. ? Brain may win out over brawn as the primary cause of breathing problems in children with a severe form of muscular dystrophy known as Pompe disease.
ATS 2009, SAN DIEGO? A protein from algae may have what it takes to stop Severe Acute Respiratory Syndrome (SARS) infections, according to new research.
A research team has pinpointed a new class of gene mutations, which identify cases of childhood acute lymphoblastic leukemia (ALL) that have a high risk of relapse and death. The finding suggests specific drugs that could treat this high-risk leukemia subtype in children, particularly because such drugs are already in clinical trials for similar blood diseases in adults.
Recycling is important not only on a global scale, but also at the cellular level, since key molecules tend to be available in limited numbers. This means a cell needs to have efficient recycling mechanisms.
Scientists may need to rethink the design of drugs meant to block HIV from infecting human cells, according to a study that appears in the May 1st issue of the journal Cell, a Cell Press publication. That's because the new report shows that HIV doesn't enter cells in the way that experts had generally assumed it did.
Several bacterial pathogens use toxins to manipulate human host cells, ultimately disturbing cellular signal transduction.
New Orleans, LA - Dr. Nicolas Bazan, Director of the Neuroscience Center of Excellence, Boyd Professor, and Ernest C. and Yvette C.
A single crafty protein allows the deadly bacterium Salmonella enterica to both invade cells lining the intestine and hijack cellular functions to avoid destruction, Yale researchers report in the April 17 issue of the journal Cell.
