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Scientists decipher missing piece of first-responder DNA repair machine

BERKELEY, CA -- Scientists from the U.S. Department of Energy's Lawrence Berkeley National Laboratory and the Scripps Research Institute have uncovered the role played by the least-understood part of a first-responder molecule that rushes in to bind and repair breaks in DNA strands, a process that helps people avoid cancer.

Electric fish plug in to communicate

AUSTIN, Texas -- Just as people plug in to computers, smart phones and electric outlets to communicate, electric fish communicate by quickly plugging special channels into their cells to generate electrical impulses, University of Texas at Austin researchers have discovered.

Trial of new treatment for advanced melanoma shows rapid shrinking of tumors

Berlin, Germany: Researchers have made significant advances in the treatment of metastatic malignant melanoma -- one of the most difficult cancers to treat successfully once it has started to spread -- according to a study to be presented at Europe's largest cancer congress, ECCO 15 -- ESMO 34 [1], in Berlin on Thursday.

All tied up: Tethered protein provides long-sought answer

HOUSTON -- (Sept. 22, 2009) -- The tools of biochemistry have finally caught up with lactose repressor protein. Biologists from Rice University in Houston and the University of Florence in Italy this week published new results about "lac repressor," which was the first known genetic regulatory protein when discovered in 1966.

New links between epilepsy and brain lipids

In mice that are missing a protein found only in the brain, neural signals "go crazy," leaving the animals with epileptic seizures from a young age, researchers have found.

Evolution still scientifically stable

An international team of researchers, including Monash University biochemists, has discovered evidence at the molecular level in support of one of the key tenets of Darwin's theory of evolution.

Prolonged stress sparks ER to release calcium stores and induce cell death in aging-related diseases

Li et al. explain how prolonged stress sparks the endoplasmic reticulum (ER) to release its calcium stores, inducing cells to undergo apoptosis in several aging-related diseases.The study will appear in the September 21, 2009 issue of the Journal of Cell Biology (online September 14).

Energy consumption makes Spanish forestry unsustainable

Spain is one of the leading European countries, along with Sweden, in terms of wood production for paper paste, but this uses large amounts of energy. Spanish and Swedish scientists have compared the environmental load stemming from forestry operations, and have concluded that the Spanish sector uses more energy than the Swedish one.

Pandemic flu can infect cells deep in the lungs, says new research

Pandemic swine flu can infect cells deeper in the lungs than seasonal flu can, according to a new study published today in Nature Biotechnology. The researchers, from Imperial College London, say this may explain why people infected with the pandemic strain of swine-origin H1N1 influenza are more likely to suffer more severe symptoms than those infected with the seasonal strain of H1N1.

Individual cells isolated from biological clock can keep daily time, but are unreliable

Alexis Webb enters a small room at Washington University in St. Louis with walls, floor and ceiling painted dark green, shuts the door, turns off the lights and bends over a microscope in a black box draped with black cloth. Through the microscope, she can see a single nerve cell on a glass cover slip glowing dimly.

The glow tells her the isolated nerve cell is busy keeping time.

MicroRNAs circulating in blood show promise as biomarkers to detect pancreatic cancer

HOUSTON - A blood test for small molecules abnormally expressed in pancreatic cancer may be a promising route to early detection of the disease, researchers at The University of Texas M. D. Anderson Cancer Center report in the September edition of the journal Cancer Prevention Research.

Finding the ZIP-code for gene therapy: Scientists imitate viruses to deliver therapeutic genes

A research report featured on the cover of the September 2009 print issue of The FASEB Journal (http://www.fasebj.org) describes how Australian scientists developed a new gene therapy vector that uses the same machinery that viruses use to transport their cargo into our cells.

Chemotherapy resistance: Checkpoint protein provides armor against cancer drugs

LA JOLLA, CA -- Cell cycle checkpoints act like molecular tripwires for damaged cells, forcing them to pause and take stock. Leave the tripwire in place for too long, though, and cancer cells will press on regardless, making them resistant to the lethal effects of certain types of chemotherapy, according to researchers at the Salk Institute for Biological Studies.

Case Western Reserve University researcher demonstrates that messenger RNA are lost in translation

CLEVELAND -- August 23, 2009 ?Case Western Reserve University School of Medicine assistant professor in the Center for RNA Molecular Biology, Jeff Coller, Ph.D., and his team discovered that messenger RNA (mRNA) predominately degrade on ribosomes, fundamentally altering a common understanding of how gene expression is controlled within the cell.

Bioplastics Industry Getting a Second Wind

August 20, 2009 by BioGeek

If anybody is thinking of updating the 1967 hit movie, The Graduate, they need to consider making a one-syllable change in the dialog. When the guy whispers in Dustin Hoffman’s ear, he needs to say: “One word. (pause) Bioplastics!" Yes, plastic made from natural polymers appears to be getting a second wind.



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