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Study finds iron levels not predictive of survival for form of blood cancer

Rochester, Minn. - May 11, 2009 - Iron chelating drugs have been heavily promoted for use in patients with primary myelofibrosis (PMF), a form of blood cancer often treated with blood transfusion. These drugs, however, which withhold available iron in the body, are highly expensive and potentially toxic.

Poor sleep quality leads to poorer prognosis after stroke

Stroke victims tend to do worse if they also have diagnosed or undiagnosed obstructive sleep apnea prior to having the stroke, according to a study presented April 28, 2009, at the American Academy of Neurology (AAN) annual meeting in Seattle.

Mayo clinic study finds gene bringing together animal and human research in alcoholism

ROCHESTER, Minn. -- An important genetic study conducted through Mayo Clinic has identified vital new information concerning alcoholism in subjects with European ancestry, according to a recent issue of Alcohol: Clinical and Experimental Research.

Mayo Clinic researchers formulate treatment combination lethal to pancreatic cancer cells

DENVER - A combination of two targeted therapies packs a powerful punch to kill pancreatic cancer cells in the laboratory, Mayo Clinic cancer researchers report.

Mayo Clinic-led researchers confirm gene variants associated with the most common adult leukemia

DENVER - A national team of researchers led by Mayo Clinic has found that patients with chronic lymphocytic leukemia (CLL) are more likely to have similar DNA changes or variants in up to six genes, compared to people who do not have the cancer.

Parkinson's disease medication triggers destructive behaviors

ROCHESTER, Minn. -- A new study conducted at Mayo Clinic reports that one in six patients receiving therapeutic doses of certain drugs for Parkinson's disease develops new-onset, potentially destructive behaviors, notably compulsive gambling or hypersexuality.

Mayo Clinic researchers discover and manipulate molecular interplay that moves cancer cells

JACKSONVILLE, Fla. -- Based on research that reveals new insight into mechanisms that allow invasive tumor cells to move, researchers at the Mayo Clinic campus in Florida have a new understanding about how to stop cancer from spreading. A cancer that spreads elsewhere in the body, known as metastasis, is the process that most often leads to death from the disease.

Mayo study shows simple finger device may help predict future heart events, such as heart attack

ORLANDO, Fla. - Results of a Mayo Clinic study show that a simple, noninvasive finger sensor test is "highly predictive" of a major cardiac event, such as a heart attack or stroke, for people who are considered at low or moderate risk, according to researchers.

Mayo Clinic study suggests those who have chronic pain may need to assess vitamin D status

ROCHESTER, Minn. -- Mayo Clinic research shows a correlation between inadequate vitamin D levels and the amount of narcotic medication taken by patients who have chronic pain. This correlation is an important finding as researchers discover new ways to treat chronic pain.

Abnormal EKG can predict death in stroke patients

People who suffer an ischemic stroke and also have an abnormality in the heart's electrical cycle are at a higher risk of death within 90 days than people who do not have abnormal electrical activity at the time of emergency treatment, according to new research.

Statins lower stroke severity, improve recovery

Mayo Clinic researchers have shown that patients who were taking statins before a stroke experienced better outcomes and recovery than patients who weren't on the drug -- even when their cholesterol levels were ideal. The finding is reported in the current issue of the Journal of Stroke and Cerebrovascular Diseases.

Measles Virus May Be Effective Prostate Cancer Treatment

Certain measles virus vaccine strain derivatives, including a strain known as MV-CEA, may prove to be an effective treatment for patients with advanced prostate cancer.

Our microbes, ourselves

In terms of diversity and sheer numbers, the microbes occupying the human gut easily dwarf the billions of people inhabiting the Earth. Numbering in the tens of trillions and representing many thousands of distinct genetic families, this microbiome, as it's called, helps the body perform a variety of regulatory and digestive functions, many still poorly understood.

Researchers Find a Key to 'Low Metabolism;' Major Factor in Obesity

Wiggle, walk, tap your toes, shop, dance, clean your basement, play the guitar to boost your NEAT -- or if you're a scientist, your "non-exercise activity thermogenesis." Mayo Clinic researchers report in today's issue of the journal Science that NEAT -- more powerful than formal exercise -- determines who is lean, and who is obese. Obese persons sit, on average, 150 minutes more each day than their naturally lean counterparts. This means obese people burn 350 fewer calories a day than do lean people.



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