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Higher levels of fatigue, distress in resident physicians linked to self-perceived medical errors

Internal medicine residents who reported higher levels of fatigue and distress were more likely to report a medical error, according to a study in the September 23/30 issue of JAMA, a theme issue on medical education.

Both distress and fatigue impact resident physician errors, Mayo study finds

ROCHESTER, Minn. -- Mayo Clinic researchers report that distress and fatigue among medical residents are independent contributors to self-perceived medical errors. The findings appear today in the Journal of the American Medical Association (JAMA).

Embargoed news from Annals of Internal Medicine

Early Release:

1. Three Medications Reduce the Risk for Invasive Breast Cancer but Carry Heavy Risks for Adverse Events

Artificial intelligence helps diagnose cardiac infections

ROCHESTER, Minn. -- Mayo Clinic researchers say that "teachable software" designed to mimic the human brain may help them diagnose cardiac infections without an invasive exam. Those findings are being presented today at the Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC) in San Francisco.

Autoimmune response can induce pancreatic tumor rejection

PHILADELPHIA -- Immune responses are capable of killing tumors before they can be directed toward normal body tissue, according to new scientific findings published in Cancer Research, a journal of the American Association for Cancer Research.

Mayo Clinic researchers find lung cancer oncogene holds key to turning off cancer stem cells

JACKSONVILLE, Fla. -- Scientists at the Mayo Clinic campus in Florida have found that the lung cancer oncogene PKCiota is necessary for the proliferation of lung cancer stem cells. These stem cells are rare and powerful master cells that manufacture the other cells that make up lung tumors and are resistant to chemotherapy treatment.

Mayo Clinic researchers find that protein believed to protect against cancer has a Mr. Hyde side

JACKSONVILLE, Fla. -- In a biological rendition of fiction's Strange Case of Dr. Jekyll and Mr. Hyde, researchers from the Mayo Clinic campus in Florida and Harvard Medical School have found that a protein thought to protect against cancer development can actually spur the spread of tumors.

Minimally invasive treatment found effective for esophageal cancer

ROCHESTER, Minn. -- Researchers have found that early stage cancers of the esophagus can be treated as effectively by less-invasive, organ-sparing endoscopic therapy as compared to more complex surgical removal of the esophagus, according to a Mayo Clinic study published in the September 2009 issue of Gastroenterology.

Mayo researchers find gene that contributes to 2 different, common neurological movement disorders

JACKSONVILLE, Fla. -- Researchers at the Mayo Clinic campus in Florida and their collaborators worldwide have discovered that a single gene promotes development of essential tremor in some patients and Parkinson's disease in others. These are two common but distinct neurological disorders.

Researchers find high-dose therapy for liver disease not effective

ROCHESTER, Minn. -- A national team of researchers led by scientists at Mayo Clinic has found that a common treatment for primary sclerosing cholangitis, a chronic liver disease, is not helpful for patients, according to a study published this month in the journal Hepatology.

Mayo Clinic Proceedings: Common blood disorder may not be linked to as many serious diseases

ROCHESTER, Minn. -- A symptomless blood disorder, monoclonal gammopathy of undetermined significance, known as MGUS, is not linked to as many serious diseases as previously thought. This finding may save patients from undergoing unnecessary workup and treatment according to a study published in the August 2009 issue of Mayo Clinic Proceedings.

Study finds adverse effects in treatment for primary sclerosing cholangitis

Primary sclerosing cholangitis (PSC) is an uncommon chronic liver disease characterized by progressive inflammation and destruction of the bile ducts. The disease progresses slowly, usually leading to biliary cirrhosis, portal hypertension and liver failure over a 10-15 year period.

2 lines account for most human embryonic stem cell research, Stanford scholar finds

STANFORD, Calif. -- For the past eight years, scientists who wanted to use federal funds for research on human embryonic stem cells had to restrict their studies to 21 cell lines approved by the National Institutes of Health. But an analysis by a researcher at the Stanford University School of Medicine suggests that only two of those lines have been used routinely.

Mayo researchers find race has role in incidence, survival of rare brain tumor

ROCHESTER, Minn. -- The incidence of a rare and deadly tumor called primary central nervous system lymphoma (PCNSL) is two times higher in black Americans, ages 20 to 49, than in white Americans, according to a Mayo Clinic study published in the June issue of Journal of Neuro-Oncology. In patients older than 49, the results were reversed.

Mayo researchers find anesthesia not harmful for babies during birth process

ROCHESTER, Minn. -- Mayo Clinic researchers have found that children exposed to anesthesia during Cesarean section are not at any higher risk for learning disabilities later in life than children not delivered by C-section.



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