St. Louis

Gut Bacteria Interact with Intestine to Regulate Blood Supply

Bacteria aren't always bad. In fact, they can be extremely helpful partners. According to research at Washington University School of Medicine in St. Louis, microbes found naturally in the mouse and human gut interact with intestinal cells, called Paneth cells, to promote the development of blood vessels in the intestinal lining. "This study provides insights into the mutually beneficial partnerships forged between mammals and their native microbes," says the principal investigator. "These symbiotic relationships probably are most important in the gut, which contains the largest and most complex collection of bacteria."

New Technique Lets Doctors Examine Milk Ducts for Breast Problems

A new technique enables doctors to directly examine the lining of milk ducts in the breast for early signs of cancer and other abnormalities, according to research at Washington University School of Medicine in St. Louis. The researchers used the technique, known as ductoscopy, to detect breast abnormalities in women with a condition called pathologic nipple discharge (PND).

Cancer drug 'smart bomb' on horizon

Today, even the best cancer treatments kill about as many healthy cells as they do cancer cells. But a St. Louis researcher has begun to lay the conceptual and experimental groundwork for a new strategy for chemotherapy -- one that turns existing drugs into medicinal "smart bombs." The approach is essentially a sophisticated drug releasing system, one that can recognize and use cancerous DNA sequences as triggering mechanisms for the drugs that fight them.

Gut Bacteria Interact with Intestine to Regulate Blood Supply

New Technique Lets Doctors Examine Milk Ducts for Breast Problems

Cancer drug 'smart bomb' on horizon

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